FAQ

Can Wellbutrin cause insomnia

By PuffBye Editorial TeamLast updated Feb 2026Based on published research from CDC, WHO & NIH

Yes, insomnia affects 15-20% of users.

Quick Answer

Yes, insomnia affects 15-20% of users.

Detailed Explanation

Take second dose no later than mid-afternoon. Sleep usually improves after first week.

Key Facts

  • Insomnia more common if taken too late in day
  • Timing adjustment resolves most sleep issues

What the Research Says

ACS recommends avoiding late-day dosing

Frequently Asked Questions

When should I take Wellbutrin
Morning and early afternoon; not after 3-4pm
Will sleep improve
Yes, as your body adjusts to medication

Sources & References

The information in this article is based on publicly available research and guidance from the following authoritative health organizations:

Sources accessed February 2026

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