FAQ
How long until nicotine is out of my system
Nicotine leaves your body within 48-72 hours.
Quick Answer
Nicotine leaves your body within 48-72 hours.
Detailed Explanation
Cotinine, a nicotine metabolite, takes 1-10 days. Full detoxification occurs within 2-3 weeks.
Key Facts
- Nicotine half-life is about 2 hours
- Cotinine is detectable for 1-10 days depending on usage
What the Research Says
CDC reports most nicotine metabolites clear within 3 days
Frequently Asked Questions
Can tests detect nicotine after 3 days
Cotinine tests may detect use for up to 10 days
Does this mean symptoms stop at 3 days
No, brain chemistry takes weeks to normalize
Sources & References
The information in this article is based on publicly available research and guidance from the following authoritative health organizations:
- CDC - Smoking & Tobacco Use
- WHO - Tobacco
- NIH - National Cancer Institute
- American Lung Association
- American Heart Association
- Truth Initiative
- Smokefree.gov
Sources accessed February 2026
Ready to Quit?
Track your progress, manage cravings, and celebrate milestones with PuffBye — the free iOS app designed to help you quit vaping and smoking for good.
