FAQ

Why am I so irritable after quitting smoking

By PuffBye Editorial TeamLast updated Feb 2026Based on published research from CDC, WHO & NIH

Nicotine withdrawal affects brain chemistry, causing mood swings and irritability.

Quick Answer

Nicotine withdrawal affects brain chemistry, causing mood swings and irritability.

Detailed Explanation

Your brain is adjusting to the absence of nicotine, which previously regulated dopamine. This typically improves within 2-4 weeks.

Key Facts

  • Irritability peaks in the first week of quitting
  • Brain chemistry normalizes within 3 months

What the Research Says

NIH studies show dopamine levels stabilize after 1 month

Frequently Asked Questions

Will I always be angry
No, mood stabilizes as brain chemistry normalizes
Can medication help irritability
Yes, some quit aids specifically target mood symptoms

Sources & References

The information in this article is based on publicly available research and guidance from the following authoritative health organizations:

Sources accessed February 2026

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